Promovita Ingredients Limited

Promovita Ingredients Limited is a wholly owned subsidiary of Dairy Crest limited, incorporated to exploit the manufacturing and sales of galacto-oligosaccharide (GOS) products for human and animal nutrition applications. Nutrabiotic® is the trademark used for animal nutrition applications.

Galacto-oligosaccharide (GOS) is a food ingredient with prebiotic properties. It is derived from bovine milk lactose in a process that includes an enzyme catalysed reaction. GOS is widely recognised to have a beneficial impact on the gut by promoting the growth and activity of bacteria that are known, or believed, to be health supporting (e.g. Bifidobacterium spp. and Lactobacillus spp.) to the detriment of bacteria that might become harmful.1 The benefits of GOS, direct or otherwise, may include the in situ provision of nutrients (e.g. short chain fatty acids), improved mineral absorption, the disruption of pathogen adhesion to gastrointestinal epithelial cells, contribution to natural defences through the promotion of beneficial interactions with the host immune system and the promotion of improved gut integrity and functional morphologies.1

Human Nutrition

GOS contains galacto-oligosaccharides that may be found in human breast milk2. These galacto-oligosaccharides also have similarities to the core structures of the oligosaccharides in human breast milk3. GOS can be added to infant formula and has been shown to aid digestive health by supporting the growth of beneficial bacteria in the colon4, 5. In partnership with Fonterra, the world's leading dairy company, Promovita Ingredients Limited supplies GOS globally to infant formula manufacturers.

Animal Nutrition

Nutrabiotic® is our brand name for GOS based animal nutrition products. Nutrabiotic® GOS, a feed material, is available for monogastric animal feed applications. There is increasing evidence that the modulation and optimization of the gut microbiota of monogastric animals by dietary intervention can improve gut health and digestive function resulting in better productivity, efficiency of feed consumption and fewer veterinary interventions.6

Contact us

To find out more about Nutrabiotic®, contact us at nutrabiotic@promovitaingredients.co.uk






References
1 - Boehm, G. and Moro, G. (2008) "Structural and Functional Aspects of Prebiotics Used in Infant Nutrition." The Journal of Nutrition 138(9) 1818S-1828S.
2 - Newburg, D.S., Ko, J.S., Leone, S. and Nanthakumar, N.N. (2016) "Human Milk Oligosaccharides and Synthetic Galactosyloligosaccharides Contain 3'-, 4-, and 6'-Galactosyllactose and Attenuate Inflammation in Human T84, NCM-460, and H4 Cells and Intestinal Tissue Ex Vivo." The Journal of Nutrition 146(2) 358-367
3 - Smilowitz, J.T., Lebrilla, C.B., Mills, D.A., German, J.B. and Freeman, S.L. (2014) "Breast Milk Oligosaccharides: Structure-Function Relationships in the Neonate." Annual Review of Nutrition 34143-169
4 - Vandenplas, Y., Greef, E.D. and Veereman, G. (2014) "Prebiotics in infant formula." Gut Microbes 5(6) 681-687
5 - Giovannini, M., Verduci, E., Gregori, D., Ballali, S., Soldi, S., Ghisleni, D. and Riva, E. (2014) "Prebiotic Effect of an Infant Formula Supplemented with Galacto-Oligosaccharides: Randomized Multicenter Trial." Journal of the American College of Nutrition 33(5) 385-393
6 - Stanley, D., Hughes, R.J. and Moore, R.J. (2014) "Microbiota of the chicken gastrointestinal tract: influence on health, productivity and disease." Applied Microbiology and Biotechnology 98(10) 301-4310



Disclaimer

This information is intended for business to business customers and health care professionals and is not meant for consumers. This information represents Promovita Ingredients' best judgement on the performance features of each ingredient and provides no warranty on the accuracy of the information presented. The term "prebiotic" is used for convenience and without implying a health claim. Any potential benefit should not be considered a health claim but may be used in the development of potential health claims in strict compliance with local legal requirements.

Promovita Ingredients Limited supports the WHO code which states that breast milk is the ideal source of nutrition for infants. Breast milk substitutes are recognised by the WHO as safe and nutritious alternatives to breast milk for infants whose mothers cannot or choose not to breast feed.